python - Can I control the mouse inside a virtual machine programatically without hijacking the cursor on my real machine? -

i trying automate html5 application checks @ location of real cursor before accepts click. tried using selenium in python automate clicks @ various points on canvas. buttons on canvas change color way supposed when mouse on them when selenium tries click on them, click accepted if have real mouse on same button @ time selenium trying click (i don't have click manually, hover mouse). so, thinking of using sikuli or autopy instead (both of have used great success in past). trouble is, both of these things move real cursor around, , don't want that.

i wonder if possible disable mouse integration virtual machine in virtualbox, , use 1 of these tools move virtual machine's cursor, , automate applications inside virtual machine without affecting real cursor. know how this, or if possible?

i have no experience selenium, maybe can make sikuli , selenium coorperate each other. 1 has wait() until parameter set. have 1 parameter, , when option "a" sikuli works, , selenium waits. , "b" other way around.